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高歌博士-副教授

发布时间:2019-10-30   浏览次数:0

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高歌,中共党员,副教授,硕士生导师。2024年6月博士毕业于中国人民大学,获得有机化学博士学位,并于同年7月入职188bet金宝博 。医用化学教研室教师,主讲本科生《有机化学》理论及实验课程。任河北省药品监督管理学会药品检验审评监管专业委员会委员。

主要科研方向为:1)AI指导抗菌药物设计与作用机制研究;2)智能响应性释放的载药体系的构建。主持河北省高等学校科学技术青年项目,河北省博士后择优资助项目,河北省博士后日常资助资等。目前以第一作者/通讯作者发表SCI论文10余篇。

主持科研项目:

1、河北省教育厅青年基金项目,QN2025336,机器学习指导抗耐药菌的三唑药物的逆向设计、合成和抗菌机制研究,5 万,2025-2027。

2、河北省博士后日常经费资助,人工智能辅助设计抗耐药菌小分子药物的活性及机制研究,12 万,2025-2027。

3、河北省燕赵黄金台聚才计划骨干人才项目,人工智能驱动双靶点抗真菌药物的 筛选及抗耐药机制研究,B2025005018,5 万。

4、188bet金宝博 博士后站科研资助第一层次,30 万。

参与科研项目:

1、国家自然科学基金青年基金,柔性氨杂环卡宾钯、镍配合物催化谐卤氟环丙烷开环选择性转化研究,30 万。

2、中国人民大学新教师启动金项目,镍催化非活泼烯烃的选择性酰化-官能化反应,24 万。

代表性论文:

1.Cuilu Quan, Peixiao Jiang, Ge Gao*, Zhiyu Wang*, Jing Wang*. Mesoporous silica-coated gold nanorod grafted with cisplatin prodrug on the surface enhances radiotherapy for cervical cancer viatriple-strategy approach. Colloids Surfaces B. 2026, 257, 115160.

2.Ge Gao, Jia-Qi Di, Hong-Yan Zhang, Li-Ping Mo* and Zhan-Hui Zhang*. A magnetic metal organic framework material as a highly efficient and recyclable catalyst for synthesis of cyclohexenone derivatives. J. Catal. 2020, 387, 39-46.

3.Ge Gao, Kuantao Mao, Leiyang Lv* and Zhiping Li*. Three-Component Coupling of α-Trifluoromethyl Carbonyls, Azides and Amines for the Regioselective Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles. Adv. Synth. Catal. 2022, 364, 1402-1408.

4.Ge Gao, Leiyang Lv* and Zhiping Li*. Three-Component Reactions of 2,2,2-Trifluoroethyl Ketones, Aryl Azides and Aqueous Ammonia for the Synthesis of 4-Cyano-1,2,3-triazoles. Eur. J. Org. Chem. 2023, e202301135.(论文被收录为“氟化学”特辑)

5.Leiyang Lv, Ge Gao, Yani Luo, Kuantao Mao and Zhiping Li* Three-Component Reactions of α-CF3 Carbonyls, NaN3, and Amines for the Synthesis of NH-1,2,3-Triazoles. J. Org. Chem. 2021, 86, 17197-17212.

6.Ge Gao and Zhiping Li* Metal-free synthesis of ketonitriles via C-F bond cleavage. New J. Chem. 2023 47, 6171-6175.

7.Gao, G.; Han, C.; Liu, Q.; Mo, L.-P.; Zhang, Z.-H. ; Photocatalytic synthesis of aryltriazenes by CulnS2/K-C3N4 heterojunctions, Mol.Catal., 2025, 572, 114764.

8.Ge Gao, Meng-Nan Chen, Li-Ping Mo* and Zhan-Hui Zhang*. Catalyst free one-pot synthesis of α-aminophosphonates in aqueous ethyl lactate. Phosphorus Sulfur Silicon Relat. Elem. 2019, 194, 528-532.

9.Ge Gao, Ping Wang, Peng Liu, Weihong Zhang, Liping Mo* and Zhanhui Zhang*. Deep Eutectic Solvent Catalyzed One-Pot Synthesis of 4,7-Dihydro-1H-pyrazolo[3,4-b] pyridine-5-carbonitriles. Chin. J. Org. Chem. 2018, 38, 846.(获得有机化学期刊年度最具影响力论文奖)

10.Ge Gao, Yi Han and Zhan-Hui Zhang* Catalyst Free Synthesis of Bis(Indolyl)Methanes and 3,3-Bis (Indolyl)oxindoles in Aqueous Ethyl Lactate. ChemistrySelect 2017, 2, 11561-11564.

11.Mo Zhang, Qiu-Yang Fu, Ge Gao, He-Ye He, Ying Zhang, Yin-Su Wu, and Zhan-Hui Zhang*. Catalyst-Free, visible-light promoted one-pot synthesis of spirooxindole-pyran derivatives in aqueous ethyl lactate. ACS Sustain Chem. Eng. 2017, 5, 6175-6182.